Endoscopic ablation of Hunner's lesions in interstitial cystitis patients. Can Urol Assoc J 2009 Dec;3(6):473-7
Date
12/19/2009Pubmed ID
20019976Pubmed Central ID
PMC2792435DOI
10.5489/cuaj.1178Abstract
INTRODUCTION: We report our experience with endoscopic ablation of Hunner's lesions in women with interstitial cystitis (IC).
METHODS: A chart review was performed on 14 patients with IC symptoms who were identified to have bladder lesions and underwent endoscopic ablation. A Hunner's lesion was identified as an area of erythema that reproduced the patients' pain when touched by the cystoscope. Pathology reports were reviewed and improvement in pain was used as the main outcome measure.
RESULTS: Of the 14 patients, 12 had more than 50% symptomatic improvement and 8 patients reported 100% improvement. Mean improvement was 76%. In all patients who improved, the biopsy specimen showed inflammatory cystitis, often with epithelial denudation. Four patients had symptomatic recurrence, but all had improvement after repeat ablation.
CONCLUSION: Endoscopic ablation of Hunner's lesions improves symptoms in IC patients. Recurrence of symptoms should prompt repeat cystoscopy to identify recurrent lesions, as repeat ablation offers symptomatic improvement.
Author List
Payne RA, O'Connor RC, Kressin M, Guralnick MLAuthors
Michael Guralnick MD Professor in the Urologic Surgery department at Medical College of WisconsinRobert Corey O'Connor MD Professor in the Urologic Surgery department at Medical College of Wisconsin
