A Case of Chronic Intranasal Cocaine Abuse Masquerading and Exacerbating Underlying Orbital IgG4-Related Disease. Ophthalmic Plast Reconstr Surg 2023 Jan-Feb 01;39(1):e11-e14
Date
07/14/2022Pubmed ID
35829663DOI
10.1097/IOP.0000000000002250Scopus ID
2-s2.0-85145641473 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Chronic cocaine use may lead to widespread intranasal inflammation and necrosis. Cases of cocaine use affecting the orbit have been reported in the literature with a clinical spectrum ranging from inflammation-induced p-anti-cytoplasmic neutrophil autoantibodies positive vasculitis to severe midline destructive lesions resulting in orbital apex syndrome. Here, we present a case of chronic intranasal cocaine abuse with midline destruction that initially obscured diagnosis of, and is hypothesized to have exacerbated, underlying IgG4-Related Disease (IgG4-RD) of the orbit over a 2-year period.
Author List
Bruce CN, Clark TJE, Ratiani M, Stahulak A, Griepentrog GJAuthors
Gregory J. Griepentrog MD Associate Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinAndrea Stahulak MD Assistant Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Chronic DiseaseCocaine
Cocaine-Related Disorders
Humans
Inflammation
