Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Human Pelvis Bayesian Injury Probability Curves From Whole Body Lateral Impact Experiments. J Eng Sci Med Diagn Ther 2020 Aug 01;3(3):031002

Date

08/01/2020

Pubmed ID

35832784

Pubmed Central ID

PMC8597554

DOI

10.1115/1.4046672

Abstract

Injury criteria are used in military, automotive, and aviation environments to advance human safety. While injury risk curves (IRCs) for the human pelvis are published under vertical loading, there is a paucity of analysis that describe IRCs under lateral impact. The objective of the present study is to derive IRCs under this mode. Published data were used from 60 whole-body postmortem human surrogate (PMHS) tests that used repeated testing protocols. In the first analysis, from single impact tests, all injury data points were considered as left censored and noninjury points were considered as right censored, while repeated testing results were treated as interval censored data. In the second analysis, injury data were treated uncensored. Peak force was used as the response variable. Age, total body mass, gender, and body mass index (BMI) were used as covariates in different combinations. Bayesian survival analysis model was used to derive the IRCs. Plus-minus 95% credible intervals (CI) and their normalized CI sizes (NCIS) were obtained. This is the first study to develop IRCs in whole body PMHS tests to describe the human pelvic tolerance under lateral impact using Bayesian models.

Author List

Yoganandan N, DeVogel N, Pintar F, Banerjee A

Authors

Anjishnu Banerjee PhD Associate Professor in the Institute for Health and Equity department at Medical College of Wisconsin
Frank A. Pintar PhD Chair, Professor in the Biomedical Engineering department at Medical College of Wisconsin
Narayan Yoganandan PhD Professor in the Neurosurgery department at Medical College of Wisconsin