Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Azoospermia in a 46,XX/47,XXX phenotypic male. Urology 1996 Dec;48(6):947-8

Date

12/01/1996

Pubmed ID

8973686

DOI

10.1016/s0090-4295(96)00321-4

Scopus ID

2-s2.0-0030454171   6 Citations

Abstract

We report the unique case of a 34-year-old 46,XX/47, XXX man with complete masculinization and azoospermia. Analysis of the patient's deoxyribonucleic acid failed to detect the azoospermia factor (AZF) region. Lack of germ cell elements on subsequent testicular biopsy illustrates the importance of the AZF region for spermatogenesis. Discussion concerning the genetics of testicular and germ cell formation is undertaken in the context of the patient presented.

Author List

Cooper CS, Sandlow JI

Author

Jay I. Sandlow MD Vice Chair, Professor in the Urologic Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Humans
Karyotyping
Male
Oligospermia
Phenotype
Sex Chromosome Aberrations
X Chromosome