Azoospermia in a 46,XX/47,XXX phenotypic male. Urology 1996 Dec;48(6):947-8
Date
12/01/1996Pubmed ID
8973686DOI
10.1016/s0090-4295(96)00321-4Scopus ID
2-s2.0-0030454171 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
We report the unique case of a 34-year-old 46,XX/47, XXX man with complete masculinization and azoospermia. Analysis of the patient's deoxyribonucleic acid failed to detect the azoospermia factor (AZF) region. Lack of germ cell elements on subsequent testicular biopsy illustrates the importance of the AZF region for spermatogenesis. Discussion concerning the genetics of testicular and germ cell formation is undertaken in the context of the patient presented.
Author List
Cooper CS, Sandlow JIAuthor
Jay I. Sandlow MD Chair, Professor in the Urologic Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultHumans
Karyotyping
Male
Oligospermia
Phenotype
Sex Chromosome Aberrations
X Chromosome