A Case of Drug-Induced Stevens-Johnson Syndrome. WMJ 2022 Oct;121(3):E63-E65
Date
10/28/2022Pubmed ID
36301663Scopus ID
2-s2.0-85140863225 (requires institutional sign-in at Scopus site)Abstract
INTRODUCTION: Stevens-Johnson syndrome is a rare but consequential and often life-threatening disorder that is most often drug-induced.
CASE PRESENTATION: An 81-year-old Black man presented with 5 days of dysphagia, odynophagia, and rash. He said he had begun a course of trimethoprim-sulfamethoxazole 6 days prior for a presumed urinary tract infection. Owing to the cutaneous lesions and punch biopsy findings, he was diagnosed with drug-induced Stevens-Johnson syndrome.
DISCUSSION: Stevens-Johnson syndrome is associated with a relatively high mortality rate. It is most commonly drug-induced and presents with extensive erythema, erosions, and blisters throughout the body.
CONCLUSIONS: Stevens-Johnson syndrome is a rare and often life-threatening disease. Early diagnosis and management is important for delivering high-quality patient care.
Author List
Lyon DR, Akinboboye O, Jain PV, Jha PAuthor
Pinky Jha MD Associate Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Aged, 80 and overHumans
Male
Stevens-Johnson Syndrome
Trimethoprim, Sulfamethoxazole Drug Combination
