Pituitary Incidentalomas: Best Practices and Looking Ahead. Endocr Pract 2023 Jan;29(1):60-68
Date
10/22/2022Pubmed ID
36270609DOI
10.1016/j.eprac.2022.10.004Scopus ID
2-s2.0-85142519548 (requires institutional sign-in at Scopus site) 3 CitationsAbstract
Pituitary Incidentalomas (PI) are pituitary lesions serendipitously identified on imaging. PIs have become common in clinical practice because of increased use of imaging and radiologic advances. The most frequently incidentally detected lesions in adults are pituitary adenomas, followed by cystic lesions, and rarely other types of tumors and infiltrative and inflammatory disorders. Biochemical screening for hyperprolactinemia and acromegaly is needed in all patients with PI, whereas testing for hyposecretion is recommended for lesions larger than 6.0 mm. Most PIs are small nonfunctioning adenomas or cysts, which can be conservatively managed. For larger lesions, a multidisciplinary approach including endocrinology, neurosurgery, and neuro-ophthalmology is required. For incidentally detected lactotroph, somatotroph, and corticotroph adenomas, disease-specific management guidelines apply. Prospective studies are needed to enhance our understanding of the long-term course and response to treatment.
Author List
Giraldi E, Allen JW, Ioachimescu AGAuthor
Adriana G. Ioachimescu MD, PhD Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ACTH-Secreting Pituitary AdenomaAcromegaly
Adenoma
Adult
Humans
Pituitary Gland
Pituitary Neoplasms
