Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Vertebral Body Bone Ablation with and without a Saline-Infused System in a Porcine Model. J Vasc Interv Radiol 2023 Apr;34(4):619-622.e1

Date

01/04/2023

Pubmed ID

36596322

DOI

10.1016/j.jvir.2022.12.475

Scopus ID

2-s2.0-85147584648 (requires institutional sign-in at Scopus site)

Abstract

The purpose of this study was to evaluate the effect of bone radiofrequency (RF) ablation in the spine with and without controlled saline infusion. RF ablation with and without controlled saline infusion was performed in the vertebral bodies of 2 swine with real-time temperature and impedance recordings. Histology and magnetic resonance (MR) imaging results were reviewed to evaluate the ablation zone size, breach of spinal canal, and damage to the spinal cord and nerves. There was no difference in maximum and mean temperatures between controlled saline and noninfusion groups. The impedance and power output were not significantly different between the groups. MR imaging and histopathology demonstrated ablation zones confined within the vertebral bodies. Ablation zone size correlated on MR imaging and histopathology by groups. No ablation effect, breach of posterior cortex, spinal cord injury, or nerve or ganglion injury was observed at any level using MR imaging or histology. Controlled saline infusion does not appear to impact bone RF ablation and, specifically, does not increase the ablation zone size.

Author List

Smolock AR, Gogineni V, Koch K, Bradley C, Tutton SM, White SB

Authors

Kevin M. Koch PhD Center Director, Professor in the Radiology department at Medical College of Wisconsin
Sarah B. White MD, MS, FSIR, FCIRSE Associate Dean, Vice Chair, Professor in the Radiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Catheter Ablation
Radio Waves
Spine
Swine
Temperature