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Practice patterns for evaluation, consent, and care of related donors and recipients at hematopoietic cell transplantation centers in the United States. Blood 2010 Jun 17;115(24):5097-101

Date

03/17/2010

Pubmed ID

20228276

Pubmed Central ID

PMC2890146

DOI

10.1182/blood-2010-01-262915

Scopus ID

2-s2.0-77954716687 (requires institutional sign-in at Scopus site)   48 Citations

Abstract

Conflict of interest may arise when 1 physician serves 2 persons whose medical care is interdependent. In hematopoietic cell transplantation (HCT) from unrelated donors and in the setting of solid organ transplantation from living donors, the standard of care is for donors and recipients to be managed by separate physicians to provide unbiased care. However, the practice patterns of evaluation and care of related donors and recipients are not well described. A survey of HCT centers in the United States was conducted by the Donor Health and Safety Working Committee of the Center for International Blood and Marrow Transplant Research to determine the type of provider involved in medical clearance, informed consent, and medical management of hematopoietic cell collection and the relationship of that provider to the HC transplant recipient. The response rate was 40%. In greater than 70% of centers, transplantation physicians were involved or potentially involved in overlapping care of the HC transplant donor and the recipient. These patterns were similar between transplantation teams caring for adult or pediatric donors and recipients. Among responding centers, medical management of recipients and their related donors by the same provider is common, a practice that has the potential for conflict of interest.

Author List

O'Donnell PV, Pedersen TL, Confer DL, Rizzo JD, Pulsipher MA, Stroncek D, Leitman S, Anderlini P, Donor Health and Safety Working Committee from Center for International Blood and Marrow Transplant Research (CIBMTR)

Author

J. Douglas Rizzo MD, MS Director, Center Associate Director, Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Child
Conflict of Interest
Donor Selection
Family
Health Care Surveys
Hematologic Neoplasms
Hematopoietic Stem Cell Transplantation
Hospital Bed Capacity
Humans
Informed Consent
Living Donors
Physician Executives
Practice Patterns, Physicians'
Surveys and Questionnaires
Transplantation, Homologous
United States