A unique paradoxical reaction to tuberculosis therapy: case report and brief review of the literature. Am J Ther 2013;20(6):e706-9
Date
12/31/2010Pubmed ID
21192247DOI
10.1097/MJT.0b013e3181fa0dc0Scopus ID
2-s2.0-84904379720 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
Extensive experience in the diagnosis and treatment of tuberculosis (TB) has led to treatment guidelines, which almost always result in progressive clinical improvement and cure in the compliant patient. Failure of a patient to respond as expected raises concerns of unexpected drug resistance, poor absorption, drug fever, or rarely an intense inflammatory reaction known as paradoxical reaction. Paradoxical reactions to anti-TB treatment are relatively rare in nonimmunocompromised individuals. Hepatic abscess is a very rare consequence of primary TB infection but has never been described as occurring as part of a paradoxical reaction. We present a case of a unique paradoxical reaction to initiation of TB treatment.
Author List
Singh B, Iqbal FM, Sunkavalli KK, Chawla BAuthor
Fahad M. Iqbal MD Staff Physician in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAntitubercular Agents
Humans
Liver Abscess
Male
Tuberculosis
