Functional magnetic resonance imaging mapping of the motor cortex in patients with cerebral tumors. Neurosurgery 1996 Sep;39(3):515-20; discussion 520-1
Date
09/01/1996Pubmed ID
8875481DOI
10.1097/00006123-199609000-00015Scopus ID
2-s2.0-0029745595 (requires institutional sign-in at Scopus site) 228 CitationsAbstract
OBJECTIVE: The purpose of this study was to determine the usefulness of functional magnetic resonance imaging (FMRI) to map cerebral functions in patients with frontal or parietal tumors.
METHODS: Charts and images of patients with cerebral tumors or vascular malformations who underwent FMRI with an echoplanar technique were reviewed. The FMRI maps of motor (11 patients), tactile sensory (12 patients), and language tasks (4 patients) were obtained. The location of the FMRI activation and the positive responses to intraoperative cortical stimulation were compared. The reliability of the paradigms for mapping the rolandic cortex was evaluated.
RESULTS: Rolandic cortex was activated by tactile tasks in all 12 patients and by motor tasks in 10 of 11 patients. Language tasks elicited activation in each of the four patients. Activation was obtained within edematous brain and adjacent to tumors. FMRI in three cases with intraoperative electrocortical mapping results showed activation for a language, tactile, or motor task within the same gyrus in which stimulation elicited a related motor, sensory, or language function. In patients with > 2 cm between the margin of the tumor, as revealed by magnetic resonance imaging, and the activation, no decline in motor function occurred from surgical resection.
CONCLUSIONS: FMRI of tactile, motor, and language tasks is feasible in patients with cerebral tumors. FMRI shows promise as a means of determining the risk of a postoperative motor deficit from surgical resection of frontal or parietal tumors.
Author List
Mueller WM, Yetkin FZ, Hammeke TA, Morris GL 3rd, Swanson SJ, Reichert K, Cox R, Haughton VMAuthors
Wade M. Mueller MD Professor in the Neurosurgery department at Medical College of WisconsinSara J. Swanson PhD Chief, Professor in the Neurology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdolescentAdult
Arousal
Astrocytoma
Brain Mapping
Brain Neoplasms
Child
Computer Graphics
Echo-Planar Imaging
Electroencephalography
Female
Frontal Lobe
Glioblastoma
Glioma
Humans
Image Processing, Computer-Assisted
Intracranial Arteriovenous Malformations
Magnetic Resonance Imaging
Male
Middle Aged
Monitoring, Intraoperative
Motor Cortex
Oligodendroglioma
Parietal Lobe
Postoperative Complications
Psychomotor Performance
Signal Processing, Computer-Assisted
Speech
Touch
