Management of monophasic synovial sarcoma of the small intestine. JSLS 2010;14(3):421-5
Date
02/22/2011Pubmed ID
21333201Pubmed Central ID
PMC3041044DOI
10.4293/108680810X12924466006846Scopus ID
2-s2.0-79951728426 (requires institutional sign-in at Scopus site) 7 CitationsAbstract
BACKGROUND: Reports of primary intraabdominal synovial sarcomas are extremely rare.
METHODS: A literature review using PubMed was performed. A retrospective review of the one known case at our institution was completed.
RESULTS: Even the most experienced pathologists report that synovial sarcomas can be very difficult to diagnose correctly. One cytogenic abnormality that is common (> 90%) and pathognomonic for synovial sarcoma is a characteristic chromosomal translocation resulting in the SYT/SSX fusion gene. Wide regional excision has been performed for intraabdominal sarcoma, with improved results. Our patient is more than 24 months with no evidence of recurrent or metastatic disease.
CONCLUSIONS: The prognosis for patients with intraabdominal synovial sarcoma remains poor. However, wide regional excision may allow for prolonged disease-free survival.
Author List
Eriksen C, Burns L, Bohlke A, Haque S, Slakey DPAuthor
Calvin Martin Eriksen MD Assistant Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultDiagnosis, Differential
Female
Follow-Up Studies
Humans
Ileal Neoplasms
Laparoscopy
Sarcoma, Synovial
Tomography, X-Ray Computed
