Inflammatory pseudotumours of the liver: a spectrum of presentation and management options. Eur J Surg Oncol 2009 Dec;35(12):1295-8
Date
06/12/2009Pubmed ID
19515527DOI
10.1016/j.ejso.2009.04.003Scopus ID
2-s2.0-70449108159 (requires institutional sign-in at Scopus site) 45 CitationsAbstract
PURPOSE: To review the current management options in inflammatory pseudotumours via analysis of ten cases from this unit the largest experience of this pathology in a Western series. To assess the medical and operative options available for this condition and the varying outcomes and the lessons learned in this unit over the time period.
RESULTS: Data from the ten cases were analysed and a comprehensive review of the published literature to date has detailed 128 case reports with 215 cases of inflammatory pseudotumour of the liver. Data analysed included patient demographics, diagnostic modalities, details of treatment and eventual outcome. The data was tabulated using an Excel spreadsheet (Microsoft Excel 2004 for Mac 2004.Version 11.0). Categorical variables were compared using Pearson's chi(2) test and p values <0.05 were defined as statistically significant. Statistical analysis was performed using SPSS for Windows (Version 9.0, SPSS Inc., Chicago, IL).
CONCLUSION: Emphasis is placed on a preferred medical management initially for this tumour with a good prognosis coupled with regular follow up. There may be a need for surgical resection cases where diagnosis is unclear or the patient is not responding to medical treatment with progression of disease or symptoms.
Author List
Goldsmith PJ, Loganathan A, Jacob M, Ahmad N, Toogood GJ, Lodge JP, Prasad KRAuthor
Kondragunta Rajendra Prasad MBBS Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedChi-Square Distribution
Child
Female
Granuloma, Plasma Cell
Humans
Liver Diseases
Male
Middle Aged
Prognosis
Young Adult