Comparison of Fibered versus Nonfibered Coils for Venous Embolization in an Ovine Model. J Vasc Interv Radiol 2023 May;34(5):888-895
Date
04/28/2023Pubmed ID
37105664DOI
10.1016/j.jvir.2022.12.481Scopus ID
2-s2.0-85152740709 (requires institutional sign-in at Scopus site) 1 CitationAbstract
PURPOSE: To compare nylon fibered (F) with nonfibered (NF) coils for embolization in an ovine venous model.
MATERIALS AND METHODS: Four- to 8-mm-diameter, 0.035-inch F and NF coils were deployed in 24 veins in 6 sheep. The number of coils, total length of the coils, and length of implanted coil pack required to achieve complete stasis were recorded, as were vessel diameter, radiation dose, ease of packing, damage to embolized vessel, and time to stasis. Venography at 1 and 3 months was used to assess the migration and durability of vessel occlusion. Veins were harvested at 3 months.
RESULTS: F and NF coils were deployed in 24 veins, and stasis was achieved, without immediate coil migration or vessel damage. The mean numbers of F and NF coils per vein were 5 and 8.75, respectively (P = .007). The vessel diameter between the groups was not statistically different. The total coil length (F, 70 cm vs NF, 122.5 cm; P = .0007), coil pack length (F, 29.3 mm vs NF, 39.4 mm; P = .003), time to stasis (F, 5.3 minutes vs NF, 9.0 minutes; P = .008), and radiation dose (F, 25.3 mGy vs NF, 34.9 mGy; P = .037) were significantly different between the groups. Challenges with the animal model prevented conclusive long-term results. Migration occurred with 8 of 11 (72%) coil packs in the femoral veins and 0 of 13 (0%) coil packs in the internal iliac and deep femoral veins. Venography demonstrated that of 16 remaining coil packs, 11 were occluded at 1 month and 10 remained occluded at 3 months.
CONCLUSIONS: Fibers allow for significantly fewer coils to achieve immediate venous occlusion.
Author List
White SB, Wissing ER, Van Alstine WG, Trerotola SOAuthor
Sarah B. White MD, MS, FSIR, FCIRSE Associate Dean, Vice Chair, Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsEmbolization, Therapeutic
Femoral Vein
Models, Animal
Phlebography
Sheep
Treatment Outcome
