Faculty Collaboration Database

Orbital MALT lymphoma with amyloid deposition. Orbit 2024 Aug;43(4):526-530

Date

05/01/2023

Pubmed ID

37125961

DOI

10.1080/01676830.2023.2203750

Scopus ID

2-s2.0-85158855788 (requires institutional sign-in at Scopus site)

Abstract

MALT lymphoma is a commonly encountered orbital tumor, and primary amyloidosis is frequently found to be an independent orbital lesion. Orbital MALT lymphoma with associated amyloid deposition is considered rare, with only 12 cases previously published. We describe a 33-year-old man, the youngest patient reported to-date, with a mass in the superonasal quadrant of the right anterior orbit. Pathology demonstrated extranodal marginal zone lymphoma in mucosa-associated lymphoid tissue with associated amyloid deposition. Systemic work-up revealed no other site of either lymphoma or amyloidosis. The patient underwent local irradiation and subsequent surgical resection of the residual mass. Persistent lymphoma was found and treated with rituximab.

Author List

Bruce CN, Kroft SH, Harris GJ

Authors

Carleigh N. Bruce MD Instructor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
Gerald J. Harris MD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
Steven Howard Kroft MD Chair, Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Amyloid
Amyloidosis
Antineoplastic Agents, Immunological
Humans
Lymphoma, B-Cell, Marginal Zone
Magnetic Resonance Imaging
Male
Orbital Neoplasms
Rituximab
Tomography, X-Ray Computed