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Neural representations of self-perception of voice: An intracortical evoked potential analysis based on an adolescent with right temporal lobe epilepsy. Seizure 2023 Jul;109:1-4

Date

05/13/2023

Pubmed ID

37172443

DOI

10.1016/j.seizure.2023.04.003

Scopus ID

2-s2.0-85159093338 (requires institutional sign-in at Scopus site)

Abstract

INTRODUCTION: The neural bases for language perception have been studied elsewhere using Transcranial Magnetic Stimulation, functional Magnetic Resonance Imaging and Direct Cortical Stimulation. However, to our knowledge, there is no previous report about a patient identifying the change in his voice tone, speed, and prosody because of right temporal cortical stimulation. Nor has there been a cortico-cortical evoked potential (CCEP) assessment of the network underlying this process.

CASE REPORT: We present CCEP from a patient with right focal refractory temporal lobe epilepsy of tumoral etiology who reported changes in the perception of his own speech prosody during stimulation. This report will serve as a complement to the understanding of the neural networks of language and prosody.

CONCLUSION: The present report shows that right superior temporal gyrus, transverse temporal gyrus, right amygdala, hippocampus, and fusiform gyrus (FG) are part of the neural network subjacent to own human voice perception.

Author List

Andrade-Machado R, Javarayee P, Koop JI, Farias-Moeller R, Kim I, Lew SM

Authors

Rene Andrade-Machado MD, PhD Assistant Professor in the Neurology department at Medical College of Wisconsin
Raquel Farias-Moeller MD Associate Professor in the Neurology department at Medical College of Wisconsin
Pradeep Javarayee MD Assistant Professor in the Neurology department at Medical College of Wisconsin
Jennifer I. Koop Olsta PhD Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Brain Mapping
Epilepsy
Epilepsy, Temporal Lobe
Evoked Potentials
Humans
Magnetic Resonance Imaging
Self Concept
Temporal Lobe