Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

Calibration of activity-related energy expenditure in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). J Sci Med Sport 2019 Mar;22(3):300-306

Date

09/05/2018

Pubmed ID

30177242

Pubmed Central ID

PMC6370477

DOI

10.1016/j.jsams.2018.07.021

Scopus ID

2-s2.0-85052826731 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

OBJECTIVES: Usual physical activity (PA) is a complex exposure and typical instruments to measure aspects of PA are subject to measurement error, from systematic biases and biological variability. This error can lead to biased estimates of associations between PA and health outcomes. We developed a calibrated physical activity measure that adjusts for measurement error in both self-reported and accelerometry measures of PA in adults from the US Hispanic Community Health Study/Study of Latinos (HCHS/SOL), a community-based cohort study.

DESIGN: Total energy expenditure (TEE) from doubly labeled water and resting energy expenditure (REE) from indirect calorimetry were measured in 445 men and women aged 18-74years in 2010-2012, as part of the HCHS/SOL Study of Latinos: Nutrition & Physical Activity Assessment Study (SOLNAS). Measurements were repeated in a subset (N=98) 6months later.

METHOD: Calibration equations for usual activity-related energy expenditure (AEE=0.90Ă—TEE-REE) were developed by regressing this objective biomarker on self-reported PA and sedentary behavior, Actical accelerometer PA, and other subject characteristics.

RESULTS: Age, weight and height explained a significant amount of variation in AEE. Actical PA and wear-time were important predictors of AEE; whereas, self-reported PA was not independently associated with AEE. The final calibration equation explained fifty percent of variation in AEE.

CONCLUSIONS: The developed calibration equations can be used to obtain error-corrected associations between PA and health outcomes in HCHS/SOL. Our study represents a unique opportunity to understand the measurement characteristics of PA instruments in an under-studied Hispanic/Latino cohort.

Author List

Shaw PA, McMurray R, Butte N, Sotres-Alvarez D, Sun H, Stoutenberg M, Evenson KR, Wong WW, Moncrieft AE, Sanchez-Johnsen LAP, Carnethon MR, Arredondo E, Kaplan RC, Matthews CE, Mossavar-Rahmani Y

Author

Lisa Sanchez-Johnsen PhD Center Associate Director, Professor in the Institute for Health and Equity department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Accelerometry
Adolescent
Adult
Aged
Calibration
Calorimetry, Indirect
Cohort Studies
Energy Metabolism
Exercise
Female
Humans
Male
Middle Aged
Models, Statistical
Self Report
Young Adult