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Flushing After Lumbar Epidural Steroid Injection with Dexamethasone. Curr Pain Headache Rep 2023 Jun;27(6):143-148

Date

04/28/2023

Pubmed ID

37115487

DOI

10.1007/s11916-023-01117-2

Scopus ID

2-s2.0-85153789815 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

PURPOSE OF REVIEW: Epidural steroid injections are an accepted treatment for low back pain and radicular symptoms. While epidural steroid injections are routinely performed without complications, side effects can be seen, including flushing. Flushing has been studied using various steroid preparations, including dexamethasone, but at significantly higher doses. This was a prospective cohort study that examines the rate of flushing in ESIs with a lower dose (4 mg) of dexamethasone. Subjects undergoing lumbar epidural steroid injection were asked about the presence of flushing following the procedure prior to discharge and again at 48 h after. A total of 80 participants received fluoroscopically guided interlaminar and transforaminal epidural injections. All participants received 4 mg of dexamethasone. Of the 80 subjects, 52 were female, and 28 were male. Seventy-one underwent a transforaminal epidural injection and 9 underwent an interlaminar epidural injection. Four (5%) subjects experienced flushing-1 subject experienced immediate post-procedural flushing and 3 experienced flushing within 48 h. All 4 subjects (100%) were female. All 4 subjects received transforaminal injections (100%).

RECENT FINDINGS: There is a gap of knowledge about the flushing after lumbar epidural steroid injection with dexamethasone. Flushing is a known and common side effect of epidural steroid injections, varying in frequency based on type of steroid as well as dose. We found 5% incidence in flushing reaction with 4 mg of dexamethasone.

Author List

Shermon S, Van Acker G, Suric V, Kim C, Abd-Elsayed A, Mata N

Author

Vladimir Suric MD Assistant Professor in the Physical Medicine and Rehabilitation department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Dexamethasone
Female
Humans
Injections, Epidural
Low Back Pain
Lumbar Vertebrae
Male
Prospective Studies
Steroids
Treatment Outcome