Demystifying Ocular Syphilis - A Major Review. Ocul Immunol Inflamm 2023 Sep;31(7):1425-1439
Date
06/12/2023Pubmed ID
37307579DOI
10.1080/09273948.2023.2217246Scopus ID
2-s2.0-85163102576 (requires institutional sign-in at Scopus site) 2 CitationsAbstract
Syphilis, caused by the spirochaete, Treponema pallidum, continues to be a public health challenge globally with its rates steadily increasing in the past few years. The disease is transmitted through small breaks in the skin during sexual contact, or via congenital transmission in utero, either across the placenta or by contact with an active genital lesion during delivery. Estimated 5.7-6 million new cases are detected every year worldwide in the 15-49 years age group. An increased incidence has been reported in most populations with particular clusters in special groups like men who have sex with men, female sex workers, and their male clients. Ocular syphilis has a varied presentation and is considered a great mimicker in all cases of uveitis. The laboratory diagnosis of syphilis is predominantly based on serological tests including TPHA and VDRL. Parenteral penicillin is the cornerstone of treatment for all stages of ocular syphilis.
Author List
Chauhan K, Fonollosa A, Giralt L, Artaraz J, Randerson EL, Goldstein DA, Furtado JM, Smith JR, Sudharshan S, Ahmed AS, Nair N, Joseph J, Pavesio C, Westcott M, Trepatchayakorn S, Sallam AB, Elhusseiny AM, Tyagi MAuthor
Edward L. Randerson MD Assistant Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
EndophthalmitisEye Infections, Bacterial
Female
Homosexuality, Male
Humans
Male
Pregnancy
Sex Workers
Sexual and Gender Minorities
Syphilis
Treponema pallidum