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The Prevalence of Penile Cancer in Patients With Adult Acquired Buried Penis. Urology 2019 Nov;133:229-233

Date

08/02/2019

Pubmed ID

31369750

DOI

10.1016/j.urology.2019.07.019

Scopus ID

2-s2.0-85071593796 (requires institutional sign-in at Scopus site)   14 Citations

Abstract

OBJECTIVE: To determine the prevalence of penile cancer in patients with adult acquired buried penis (AABP). Penile cancer is a rare but aggressive cancer. Several case reports have recently been published that indicate that AABP may increase the risk of penile cancer.

MATERIALS AND METHODS: A retrospective review was conducted of adults diagnosed with AABP and penile cancer between January, 2008 and December, 2018 seen at a tertiary referral center. Demographics including age, BMI, comorbidities, etiology of AABP, smoking history, circumcision status, and premalignant lesions (condyloma, lichen sclerosus [LS] carcinoma in situ [CIS]) were recorded. For patients with penile cancer, AJCC staging, grade, TNM staging and treatments were recorded. Basic descriptive statistics were performed for the overall cohort. We used Chi-square tests and Fisher exact tests to compare differences between patients with benign pathology and patients with malignant or pre-malignant pathology.

RESULTS: We identified 150 patients with the diagnosis of AABP. The prevalence of penile squamous cell carcinoma was 7%. There was a 35% rate of premalignant lesions. This study is limited by its retrospective and single-institution nature.

CONCLUSION: AABP is a condition that incorporates multiple risk factors for penile cancer. The prevalence of penile cancer appears to be higher in patients with AABP; however, more data are needed to confirm these initial findings. Patients with AABP should be counseled on these risks and should be considered for buried penis repair if a physical examination cannot be performed.

Author List

Pekala KR, Pelzman D, Theisen KM, Rogers D, Maganty A, Fuller TW, Rusilko PJ

Author

Daniel Pelzman MD Instructor in the Urologic Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adult
Humans
Male
Middle Aged
Obesity
Penile Diseases
Penile Neoplasms
Prevalence
Retrospective Studies