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Multifocal vulvar smooth muscle tumor with an unusual intravascular growth pattern and multiple local recurrences in a 10-year-old child: a diagnostic dilemma. Pediatr Dev Pathol 2011 May-Jun;14(3):235-9

Date

11/26/2010

Pubmed ID

21090988

DOI

10.2350/09-10-0730-CR.1

Scopus ID

2-s2.0-80054051952   1 Citation

Abstract

Smooth muscle tumors of the vulva are rare entities with variable morphologic features and clinical behavior. Our report summarizes the case of a multifocal vulvar smooth muscle tumor of undetermined malignant potential with an unusual intravascular growth pattern and subsequent local recurrence in a 10-year-old girl, the youngest case reported to date, and reviews the specific pathologic findings of that category. Vulvar smooth muscle tumors of undetermined malignant potential represent a diagnostic, prognostic, and therapeutic challenge. The histologic features of this case were predictive of local recurrence, although the significance of the intravascular growth pattern is still uncertain. The relationship of this multifocal, recurrent tumor to the clinical entity, vulvar leiomyomatosis, is unknown at this time.

Author List

Harrington A, Bell E, Suchi M, Behmaram B, Uyar D

Authors

Alexandra M. Harrington MD Professor in the Pathology department at Medical College of Wisconsin
Mariko Suchi MD, PhD Associate Professor in the Pathology department at Medical College of Wisconsin
Denise S. Uyar MD Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Child
Female
Humans
Neoplasm Recurrence, Local
Smooth Muscle Tumor
Vulvar Neoplasms
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a