Multifocal vulvar smooth muscle tumor with an unusual intravascular growth pattern and multiple local recurrences in a 10-year-old child: a diagnostic dilemma. Pediatr Dev Pathol 2011;14(3):235-9
Date
11/26/2010Pubmed ID
21090988DOI
10.2350/09-10-0730-CR.1Scopus ID
2-s2.0-80054051952 (requires institutional sign-in at Scopus site) 1 CitationAbstract
Smooth muscle tumors of the vulva are rare entities with variable morphologic features and clinical behavior. Our report summarizes the case of a multifocal vulvar smooth muscle tumor of undetermined malignant potential with an unusual intravascular growth pattern and subsequent local recurrence in a 10-year-old girl, the youngest case reported to date, and reviews the specific pathologic findings of that category. Vulvar smooth muscle tumors of undetermined malignant potential represent a diagnostic, prognostic, and therapeutic challenge. The histologic features of this case were predictive of local recurrence, although the significance of the intravascular growth pattern is still uncertain. The relationship of this multifocal, recurrent tumor to the clinical entity, vulvar leiomyomatosis, is unknown at this time.
Author List
Harrington A, Bell E, Suchi M, Behmaram B, Uyar DAuthors
Alexandra M. Harrington MD Professor in the Pathology department at Medical College of WisconsinMariko Suchi MD, PhD Professor in the Pathology department at Medical College of Wisconsin
Denise S. Uyar MD Professor in the Obstetrics and Gynecology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
ChildFemale
Humans
Neoplasm Recurrence, Local
Smooth Muscle Tumor
Vulvar Neoplasms
