Faculty Collaboration Database

Clonidine in the treatment of brainstem spasticity. Case report. Am J Phys Med Rehabil 1992 Oct;71(5):301-3

Date

10/01/1992

Pubmed ID

1388979

DOI

10.1097/00002060-199210000-00010

Scopus ID

2-s2.0-0026671069 (requires institutional sign-in at Scopus site)   19 Citations

Abstract

This report describes a patient who developed spasticity after a medullary infarct. No improvement in her spasticity was achieved by baclofen therapy and the side effects of the drug necessitated its gradual withdrawal. Recent reports of the success of clonidine in the management of spasticity due to spinal cord injury prompted an attempt at clonidine therapy. When clonidine therapy was initiated, the patient responded rapidly with both subjective and objective improvements in her spasticity. This case suggests a potential role for clonidine in the treatment of spasticity resulting from brainstem infarction.

Author List

Sandford PR, Spengler SE, Sawasky KB

Author

Kathleen B. Sawasky MD Assistant Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Baclofen
Cerebral Infarction
Clonidine
Female
Humans
Medulla Oblongata
Muscle Spasticity
Quadriplegia