Comparison of patients with early-, typical-, and late-onset affective psychosis. Am J Psychiatry 1997 Sep;154(9):1299-301
Date
09/01/1997Pubmed ID
9286193DOI
10.1176/ajp.154.9.1299Scopus ID
2-s2.0-0030864208 (requires institutional sign-in at Scopus site) 28 CitationsAbstract
OBJECTIVE: The authors compared the clinical characteristics and family history of patients with early-onset (before age 18), typical-onset (at 20-25 years), and late-onset (after age 35) affective psychosis at the time of first hospitalization.
METHOD: Diagnostic, symptom, and family history information was obtained from 88 consecutively hospitalized patients.
RESULTS: Major depression was more common in the late-onset group, and a family history of affective and substance abuse disorders was more common among the early-onset patients. Affective symptoms differed significantly among groups; specifically, early-onset patients had more energy, minimal sleep disruption, and greater suicidality, while typical-onset patients had more severe abnormal thought content.
CONCLUSIONS: Among patients with affective psychosis, there may be heterogeneity of symptoms and family history associated with age at first hospitalization.
Author List
Sax KW, Strakowski SM, Keck PE Jr, McElroy SL, West SA, Bourne ML, Larson ERAuthor
Eric Larson PhD Associate Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentAdult
Affective Disorders, Psychotic
Age of Onset
Bipolar Disorder
Comorbidity
Depressive Disorder
Family
Female
Hospitalization
Humans
Male
Prevalence
Psychiatric Status Rating Scales
Severity of Illness Index
Sleep Wake Disorders
Substance-Related Disorders
Suicide
