Faculty Collaboration Database

The use of venous jump grafts in pancreatic transplantation - no difference in patient or allograft outcomes - an update of the UNOS database. Clin Transplant 2014 Aug;28(8):883-8

Date

06/17/2014

Pubmed ID

24930804

DOI

10.1111/ctr.12397

Scopus ID

2-s2.0-84906101182 (requires institutional sign-in at Scopus site)   9 Citations

Abstract

Venous jump grafts are used in pancreas transplantation to salvage a pancreas with a short portal vein or to facilitate an easier anastomosis. There have been no large studies evaluating the safety of venous jump grafts in pancreas transplantation. We analyzed the UNOS database to determine whether venous jump grafts are associated with graft loss or patient death. Data from UNOS on all adult pancreas transplant recipients 1996-2012 were analyzed. Venous extension grafts were used in 2657 cases; they were not in 18 124. Kaplan-Meier/product-limit estimates analysis demonstrated similar patient survival (p < 0.641) and death-censored graft survival (p < 0.351) at one, three, five,10, and 15 yr between subjects with and without venous jump grafts. There was a statistically significant difference in one-yr unadjusted patient survival between the venous extension graft (94.9%) and the no-venous extension graft (95.8%) groups (p < 0.045) and a borderline difference in one-yr graft survival between the venous extension graft (84.1%) and the no-venous extension graft (82.6%) groups (p < 0.055). There was no significant difference in patient survival or allograft survival at the three-, five-, 10-, and 15-yr intervals. The use of venous jump grafts is not associated with increased graft loss or mortality.

Author List

Siskind E, Maloney C, Ashburn S, Akerman M, Siskind T, Goldberg L, Bhaskaran M, Basu A, Molmenti E, Ortiz J

Author

Caroline Maloney MD, PhD Assistant Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Anastomosis, Surgical
Databases, Factual
Female
Follow-Up Studies
Graft Rejection
Graft Survival
Humans
Male
Pancreas Transplantation
Pancreatic Diseases
Portal Vein
Prognosis
Risk Factors
Survival Rate
Transplantation, Homologous
Venous Thrombosis