Functional MR activation correlated with intraoperative cortical mapping. AJNR Am J Neuroradiol 1997 Aug;18(7):1311-5
Date
08/01/1997Pubmed ID
9282861Pubmed Central ID
PMC8338039Scopus ID
2-s2.0-0031546115 (requires institutional sign-in at Scopus site) 225 CitationsAbstract
PURPOSE: To evaluate the spatial specificity of functional MR imaging by comparing it with intraoperative electrocortical mapping.
METHODS: Functional MR imaging was performed in 28 patients before awake craniotomy and intraoperative electrocortical mapping. Activation was mapped for finger movement, lip movement, tongue movement, word generation, and counting paradigms. During surgery, finger movement, lip movement, tongue movement, counting, and/or speaking were mapped. The functional images and the photographic recordings of the brain functions mapped during surgery were converted to bit maps and coregistered by a computer program. The distance between the intraoperatively mapped function site and the MR activation site for a comparable function was measured.
RESULTS: Forty-six functions were recorded on MR images and intraoperative maps. In 100% of correlations, the intraoperative site and the MR activation site were within 20 mm; in 87% of correlations they were within 10 mm. For each paradigm, 67% or more of the intraoperative stimulation maps correlated within 10 mm of the MR activation site.
CONCLUSIONS: For the tasks used in this study, the activation site on functional MR images correlated well with the site at which intraoperative stimulation identified function.
Author List
Yetkin FZ, Mueller WM, Morris GL, McAuliffe TL, Ulmer JL, Cox RW, Daniels DL, Haughton VMAuthors
Timothy L. McAuliffe PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinWade M. Mueller MD Professor in the Neurosurgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Afferent PathwaysBrain Mapping
Brain Neoplasms
Cerebral Cortex
Computer Graphics
Dominance, Cerebral
Echo-Planar Imaging
Electroencephalography
Epilepsy
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Imaging
Monitoring, Intraoperative
Motor Activity
Mouth
Postoperative Complications
Psychosurgery
Signal Processing, Computer-Assisted
Thinking
Tongue
Verbal Behavior
