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Successful pulmonary artery embolectomy in a patient with a saddle Wilms tumor embolus. Pediatr Blood Cancer 2012 May;58(5):806-9

Date

06/18/2011

Pubmed ID

21681933

DOI

10.1002/pbc.23215

Scopus ID

2-s2.0-84857881778 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

Denys-Drash syndrome is a genetic disorder characterized by ambiguous genitalia, cryptorchidism, nephrotic syndrome, and a high predilection for Wilms tumor with intravascular invasion. We report a 5-year-old male with Denys-Drash syndrome who rapidly developed Wilms tumor with vascular invasion, subsequent saddle tumor embolus, and required emergent embolectomy. This case illustrates the rapid emergence of Wilms tumor in a patient with Denys-Drash syndrome and the importance of considering embolectomy over thrombolytic therapy for PE in this population, given a high likelihood of tumor embolus.

Author List

Cooper L, Moore C, Branchford B, Greffe B, Capocelli K, Kuder A, Mehta I, Mourani PM

Author

Brian Branchford MD Associate Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Child, Preschool
Denys-Drash Syndrome
Embolectomy
Humans
Kidney Neoplasms
Male
Pulmonary Artery
Pulmonary Embolism
Wilms Tumor