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Revision Targeted Muscle Reinnervation Improves Secondary Pain Insult in an Upper Extremity Amputee: A Case Report. Hand (N Y) 2021 Nov;16(6):NP15-NP18

Date

02/18/2021

Pubmed ID

33593099

Pubmed Central ID

PMC8647333

DOI

10.1177/1558944721992467

Scopus ID

2-s2.0-85100876712 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

Targeted muscle reinnervation (TMR) has been shown to improve phantom and neuropathic pain in both the acute and chronic amputee population. Through rerouting of major peripheral nerves into a newly denervated muscle, TMR harnesses the plasticity of the brain, helping to revert the sensory cortex back toward the preinsult state, effectively reducing pain. We highlight a unique case of an above-elbow amputee for sarcoma who was initially treated with successful transhumeral TMR. Following inadvertent nerve biopsy of a TMR coaptation site, his pain returned, and he was unable to don his prosthetic. Revision of his TMR to a more proximal level was performed, providing improved pain and function of the amputated arm. This is the first report to highlight the concept of secondary neuroplasticity and successful proximal TMR revision in the setting of multiple insults to the same extremity.

Author List

Rivedal DD, Guo M, Sanger J, Morgan A

Author

David Rivedal MD Assistant Professor in the Plastic Surgery department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Amputees
Humans
Male
Muscle, Skeletal
Phantom Limb
Upper Extremity