Faculty Collaboration Database

The role of dental prostheses in alveolar ridge squamous carcinomas. Arch Otolaryngol Head Neck Surg 1997 Oct;123(10):1112-5

Date

10/27/1997

Pubmed ID

9339989

DOI

10.1001/archotol.1997.01900100088012

Scopus ID

2-s2.0-0030729058 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

BACKGROUND: Alveolar ridge squamous carcinomas develop in patients outside the usual constellation of risk factors.

OBJECTIVE: To determine whether the use of dentures was a risk factor specific to patients with alveolar ridge carcinoma.

DESIGN: Case-control method with a unique control group-a concurrent cohort of patients with head and neck cancer with primaries in the oropharynx, hypopharynx, and larynx.

SETTING: Tertiary care hospital-based clinic.

PATIENTS: Forty-one patients with squamous carcinomas centered on the maxillary or mandibular alveolar ridges. The control group was 175 concurrently seen patients with squamous carcinomas of the laryngopharynx for whom dental status was known.

MAIN OUTCOME MEASURES: Age at diagnosis, sex, tobacco use, alcohol use, and denture use.

RESULTS: Patients with alveolar ridge were more likely to be female, older, nonsmokers, and nondrinkers. The crude odds ratio of denture use in patients with alveolar ridge cancer was 2.28 (P=.03). Eliminating other confounding factors with logistic regression, the adjusted odds ratio dropped to 1.30 (P=.59). Among patients with alveolar ridge, smoking status correlated with age and gender: current smokers were on average 64.4 years old and 9 of 16 were men. Nonsmokers' average age was 79.1 years and 1 of 11 was a man.

CONCLUSIONS: In this study, denture use was not an independent risk factor for alveolar ridge carcinomas. Among patients with little to no tobacco or alcohol exposure, the alveolar ridge carcinomas tended to occur in the elderly and in women.

Author List

Campbell BH, Mark DH, Soneson EA, Freije JE, Schultz CJ

Authors

Bruce H. Campbell MD Emeritus Professor in the Otolaryngology department at Medical College of Wisconsin
Christopher J. Schultz MD Chair, Professor in the Radiation Oncology department at Medical College of Wisconsin
Eric A. Soneson MD Staff Physician in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aged
Alcohol Drinking
Carcinoma, Squamous Cell
Case-Control Studies
Dental Prosthesis
Female
Gingival Neoplasms
Head and Neck Neoplasms
Humans
Logistic Models
Male
Middle Aged
Risk Factors
Smoking