Faculty Collaboration Database

Neuroscience: Visual restoration with optogenetics. Curr Biol 2023 Feb 06;33(3):R110-R112

Date

02/08/2023

Pubmed ID

36750022

DOI

10.1016/j.cub.2022.12.052

Scopus ID

2-s2.0-85147627541 (requires institutional sign-in at Scopus site)

Abstract

Treating photoreceptor degenerative diseases is an exciting application of optogenetic technologies. However, there are significant challenges, such as producing normal visual signaling as the retina rewires in response to photoreceptor death. However, a new study shows remarkable functional stability in retinal circuits that can be engaged by optogenetics following photoreceptor loss.

Author List

Scalabrino ML, Field GD

Author

Miranda L. Scalabrino PhD Assistant Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Humans
Neurosciences
Optogenetics
Photoreceptor Cells
Retina
Retinal Degeneration