Sensitivity of Two-Tiered Lyme Disease Serology in Children With an Erythema Migrans Lesion. J Pediatric Infect Dis Soc 2023 Oct 28;12(10):553-555
Date
09/27/2023Pubmed ID
37756491DOI
10.1093/jpids/piad073Scopus ID
2-s2.0-85175356902 (requires institutional sign-in at Scopus site)Abstract
In our prospective cohort of 192 children with a physician-diagnosed erythema migrans (EM) lesion, two-tier Lyme disease serology had higher sensitivity in children with multiple EM lesions (76.8% multiple lesions vs. 38.1% single EM; difference 38.7%, 95% confidence interval 24.8%-50.4%). The diagnosis of cutaneous Lyme disease should be based on careful physical examination rather than laboratory testing.
Author List
Thompson AD, Balamuth F, Neville DN, Chapman LL, Levas MN, Kharbanda AB, Branda JA, Ladell MM, Loiselle C, Nigrovic LEAuthors
Meagan Ladell MD Assistant Professor in the Pediatrics department at Medical College of WisconsinMichael Levas MD Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
ChildErythema Chronicum Migrans
Humans
Lyme Disease
Prospective Studies