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Sensitivity of Two-Tiered Lyme Disease Serology in Children With an Erythema Migrans Lesion. J Pediatric Infect Dis Soc 2023 Oct 28;12(10):553-555

Date

09/27/2023

Pubmed ID

37756491

DOI

10.1093/jpids/piad073

Scopus ID

2-s2.0-85175356902 (requires institutional sign-in at Scopus site)

Abstract

In our prospective cohort of 192 children with a physician-diagnosed erythema migrans (EM) lesion, two-tier Lyme disease serology had higher sensitivity in children with multiple EM lesions (76.8% multiple lesions vs. 38.1% single EM; difference 38.7%, 95% confidence interval 24.8%-50.4%). The diagnosis of cutaneous Lyme disease should be based on careful physical examination rather than laboratory testing.

Author List

Thompson AD, Balamuth F, Neville DN, Chapman LL, Levas MN, Kharbanda AB, Branda JA, Ladell MM, Loiselle C, Nigrovic LE

Authors

Meagan Ladell MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
Michael Levas MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Child
Erythema Chronicum Migrans
Humans
Lyme Disease
Prospective Studies