Faculty Collaboration Database

Ipsilateral versus contralateral placement of the pancreas allograft in pancreas after kidney transplant recipients. Clin Transplant 2018 Aug;32(8):e13337

Date

06/29/2018

Pubmed ID

29952108

DOI

10.1111/ctr.13337

Scopus ID

2-s2.0-85050507144 (requires institutional sign-in at Scopus site)   5 Citations

Abstract

BACKGROUND: In a diabetic, uremic kidney transplant recipient that may receive a future pancreas after kidney (PAK) transplant, the kidney is typically implanted on the left side in anticipation of the subsequent pancreas transplant on the right side. In this study, we sought to determine if ipsilateral PAK (iPAK) is as safe as contralateral PAK (cPAK).

METHODS: The 115 PAK transplants (iPAK n = 57, cPAK n = 58) were performed from 1997-2010 and results were compared between the groups.

RESULTS: Kidney graft survival and pancreas graft survival was similar between the two groups. Kidney graft function according to serum creatinine and eGFR was not different between the cPAK and the iPAK groups and there were no episodes of kidney graft thrombosis in either group. Subgroup analyses focusing on donor source also did not show worse outcomes for graft survivals in iPAK group when compared to cPAK group.

CONCLUSIONS: Pancreas and kidney graft survival in PAK transplants is unaffected by the surgical procedure and iPAK is safe.

Author List

Yin H, Arpali E, Leverson GE, Sollinger HW, Kaufman DB, Odorico JS

Author

Emre Arpali MD, PhD Associate Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Allografts
Diabetes Mellitus, Type 1
Diabetic Nephropathies
Female
Follow-Up Studies
Graft Survival
Humans
Kidney Transplantation
Male
Pancreas Transplantation
Postoperative Complications
Prognosis
Retrospective Studies
Risk Factors
Survival Rate