Faculty Collaboration Database

Evaluation of the upper esophageal sphincter (UES) using simultaneous high-resolution endoluminal sonography (HRES) and manometry. Dig Dis Sci 2004 May;49(5):703-9

Date

07/21/2004

Pubmed ID

15259487

DOI

10.1023/b:ddas.0000030077.15625.69

Scopus ID

2-s2.0-3042761015 (requires institutional sign-in at Scopus site)   17 Citations

Abstract

The aim of this study was to characterize the motion, morphology, and pressure of the upper esophageal sphincter (UES). The UES and its surrounding structures were evaluated in seven normal subjects and four human cadavers, using simultaneous high-resolution endoluminal sonography and manometry. The UES musculature on ultrasound is a C-shaped structure with an angle of 107 +/- 19 degrees. The mean peak resting UES pressure was 74 mm Hg, with a total cross-sectional area (CSA) of 0.87 +/- 0.33 cm2. During swallowing, the UES moved in an orad direction. Localizing the UES sonographically, the peak UES pressure in the cadavers was 19.7 +/- 10.0 mm Hg. The UES has a greater muscular CSA and resting pressure than the upper esophageal body. In the cadaver studies, the UES was imaged in conjunction with a significant increase in pressure, indicating that the pressure is due to passive mechanical conformational changes.

Author List

Miller LS, Dai Q, Sweitzer BA, Thangada V, Kim JK, Thomas B, Parkman H, Soliman AM

Author

Beje Thomas MD Associate Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Deglutition
Endosonography
Esophagogastric Junction
Female
Gastrointestinal Motility
Humans
Male
Manometry
Pressure
Rest