Faculty Collaboration Database

Predictors of lean body mass and total adipose mass in community-dwelling elderly men and women. Am J Med Sci 1998 Mar;315(3):188-93

Date

03/31/1998

Pubmed ID

9519932

DOI

10.1097/00000441-199803000-00008

Scopus ID

2-s2.0-0031895248 (requires institutional sign-in at Scopus site)   37 Citations

Abstract

As part of an ongoing longitudinal study, we analyzed cross-sectional data to identify the predictors of lean body mass (LBM) and total adipose mass (TAM) in community-dwelling elderly men and women. Body composition analysis was done using dual energy x-ray absorptiometry. A total 262 subjects (118 women and 144 men), 60 to 80 years of age, from the urban and suburban communities of southeastern Wisconsin were studied. In women, the age (r = -.18), body mass index (BMI) (r = .43), and waist-to-hip ratio (WHR) (r = .30), and in men, BMI (r = .45) and insulin-like growth factor-1 (IGF-1) (r = .32) were identified as predictors (P < .05) of LBM. In women, the BMI (r = .87), WHR (r = .21), and functional work capacity (VO2 max) (r = -.47), and in men, the BMI (r = .83), WHR (r = .52), dehydroepiandrosterone sulfate (DHEAS) (r = -.27), total testosterone (TT) (r = -.35), free testosterone (FT) (r = -.23), physical activity (LTE) (r = -.32), and VO2 peak (r = -.59) were identified as predictors of TAM. After partialling out age in addition to the predictors identified earlier, the VO2 peak was identified as a predictor (P < .05) of LBM in both women and men, and TT, FT, and LTE as predictors (P < .05) of LBM in men. We conclude that the BMI, WHR, and VO2 peak influences LBM and TAM in both women and men. Additionally, in men LBM and TAM is influenced by hormone profile.

Author List

Abbasi AA, Mattson DE, Duthie EH Jr, Wilson C, Sheldahl L, Sasse E, Rudman IW

Author

Edmund H. Duthie MD Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Absorptiometry, Photon
Adipose Tissue
Aged
Aging
Body Composition
Body Constitution
Body Mass Index
Cholesterol
Dehydroepiandrosterone Sulfate
Estrogen Replacement Therapy
Female
Humans
Insulin-Like Growth Factor I
Longitudinal Studies
Male
Middle Aged
Oxygen Consumption
Sex Characteristics
Testosterone