Assessment of infant gonadal dose irradiated from urine-contaminated diapers during diuretic renal scintigraphy. Nucl Med Commun 2024 Jan 01;45(1):45-50
Date
10/30/2023Pubmed ID
37901921DOI
10.1097/MNM.0000000000001783Scopus ID
2-s2.0-85179806918 (requires institutional sign-in at Scopus site)Abstract
OBJECTIVE: To estimate the gonadal doses irradiated from urine- contaminated diapers during diuretic renal scintigraphy.
METHODS: Images of 31 patients (18 males and 13 females) with urine-contaminated diapers during 99m Tc-MAG3 renal scintigraphy were analyzed. The count rate of the diapers was converted into a time-activity curve based on the calibrated factor of the gamma camera system. The cumulative activity was determined from the area under the curve. By incorporating dose per unit cumulative activity pre-calculated from Monte Carlo simulation with 0-year phantom, the gonadal dose irradiated from diaper was calculated. To assess the degree of this additionally introduced dose from diapers, the calculated gonadal dose was compared to the internal gonadal dose from injected radiotracer activity.
RESULTS: The cumulative activities irradiated from urine-contaminated diapers were 1.12 E04 ± 1.29E04 MBq.s in male infants, which was nearly half of the 1.94 E04 ± 1.80E04 MBq.s ( P = 0.15) in female infants. However, the absorbed doses for testes in male infants were 7.37E-01 ± 8.50E-01 mGy, which was approximately 10 times the 6.38E-02 ± 5.94E-02 mGy for ovaries in female infants ( P < 0.01). The diaper-introduced dose for testes and ovaries was 91.7% and 3.9% of the gonadal doses from the injected activity in patients with normal renal function, and 99.0% and 4.3% of those in patients with abnormal renal function.
CONCLUSION: Urine-contaminated diapers introduced additional radiation doses to infant patients during 99m Tc-MAG3 renal scintigraphy. The gonadal doses were of significance in male infants who had nearly double the absorbed dose for the testes.
Author List
Lu Y, Kumbhar S, Liu Y, Vo NJ, Lu J, Baker M, Qi JAuthor
Yonggang Lu PhD Assistant Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ChildDiuretics
Female
Humans
Infant
Infant Care
Male
Radionuclide Imaging
Technetium Tc 99m Mertiatide
