Effects of marijuana history on the subjective, psychomotor, and reinforcing effects of nitrous oxide in humans. Drug Alcohol Depend 1994 Dec;36(3):227-36
Date
12/01/1994Pubmed ID
7889814DOI
10.1016/0376-8716(94)90149-xScopus ID
2-s2.0-0027986910 (requires institutional sign-in at Scopus site) 15 CitationsAbstract
An experiment using marijuana users and non-users was conducted to assess whether the reinforcing, subjective, or psychomotor effects of nitrous oxide were influenced by a subject's drug history. Subjects in the first four sessions sampled 40% nitrous oxide in oxygen and 100% oxygen (placebo), and then over the next three sessions, chose which agent they wished to inhale. Choice distributions between the two groups did not differ significantly, and nitrous oxide choice rates were less than 50% in both groups. However, a history of marijuana use appeared to intensify some of the subjective effects induced by nitrous oxide inhalation.
Author List
Yajnik S, Thapar P, Lichtor JL, Patterson T, Zacny JPAuthor
Santosh Yajnik MD Associate Professor in the Radiation Oncology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Administration, InhalationAdult
Affect
Arousal
Attention
Female
Humans
Male
Marijuana Abuse
Motivation
Neuropsychological Tests
Nitrous Oxide
Personality Inventory
Psychomotor Performance
