Radio-frequency ablation of large, nonresectable hepatic tumors. Am Surg 2004 Dec;70(12):1035-8
Date
01/25/2005Pubmed ID
15663040Scopus ID
2-s2.0-13844316810 (requires institutional sign-in at Scopus site) 6 CitationsAbstract
Patients with nonresectable hepatic metastases who are not treated survive an average of 6 months. We report our experience with radio-frequency ablation (RFA) of nonresectable hepatic tumors 4 cm or greater in size. A retrospective chart review of all patients undergoing RFA of hepatic tumors 4 cm or greater from October 1, 1999, through August 31, 2002, was performed. Thirty-six patients were identified who underwent RFA of tumors 4 cm or greater. There were a total of 81 tumors ablated in the 36 patients. Twenty patients underwent RFA only; seven patients received RFA plus a wedge resection. Five patients were treated with RFA followed by chemoembolization. Two patients underwent RFA plus placement of a hepatic artery infusion pump. The median tumor size was 5 cm (range, 4-14 cm). Median patient follow-up was 26 months (range, 1-54 months). Patients with metastatic colon cancer had the longest median survival of 28 months (range, 1 and 48 months). The survival of primary hepatocellular carcinoma was worse with a median survival of 20 months (range, 1-36 months). At last follow-up, 11 (30%) of the patients remain alive and disease free. There were no perioperative deaths and one intraoperative complication. In our experience, RFA of larger tumors is effective and safe. Tumor size should not be an absolute contraindication to RFA of nonresectable hepatic tumors.
Author List
Morgan JH 3rd, Royer GM, Hackett P, Gamblin TC, McCampbell BL, Conforti A, Dale PSAuthor
Thomas Clark Gamblin MD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAged
Catheter Ablation
Combined Modality Therapy
Female
Humans
Liver Neoplasms
Male
Middle Aged
Neoplasm Staging
Retrospective Studies
Survival Analysis
Treatment Outcome
