A Global Overview on the Evolution, Debate, and Research Output on Liver Transplant Perfusion Machines. Exp Clin Transplant 2024 Jan;22(1):35-42
Date
01/29/2024Pubmed ID
38284373DOI
10.6002/ect.2023.0180Scopus ID
2-s2.0-85183713565 (requires institutional sign-in at Scopus site)Abstract
OBJECTIVES: Machine perfusion of liver grafts has gained popularity for its abilities to preserve liver grafts,reduce cold storage damage, and evaluate graft viability before transplant. However, debate persists regarding the optimal solutions, logistics, and biomarkers for assessing graft quality. To shed light on the lengthy debates surrounding the use of machine perfusion in liver graft preservation,this study utilized bibliometric analysis to evaluate the status and development trends of main research areas.
MATERIALS AND METHODS: On December 10th, 2022, we conducted a literature search using the Web of Science database to identify articles related to liver machine perfusion. The search included only original studies and reviews and excluded meeting abstracts, letters, notes, editorials, short surveys, book chapters, and errata. We identified the number of citations and encompassed various aspects, such as annual trends, countries, institutions, authors, journals, and key words. We used VOSviewer version 1.6.18 to generate tables and figures.
RESULTS: After manually removing irrelevant papers, we included 264 articles (89 reviews; remaining were original studies). The articles were cited 5743 times, averaging 21.92 per article. We found that the United Kingdom (n = 76) was the country that produced the most articles,followed by theUnited States (66 articles). Most papers in our search were published in Liver Transplantation (n = 31) and Transplantation (n = 16).
CONCLUSIONS: Bibliometric analysis provided insights into debates and advancements in liver graft preservation using machine perfusion. The analysis showed leading countries and key research areas in the field. This overview serves as a valuable resource for researchers, offering a foundation for further exploration and guiding future investigations in the field of machine perfusion for liver graft preservation.
Author List
Rawashdeh B, Kim J, Prasad R, Cooper MAuthors
Matthew Cooper MD Chief, Director, Professor in the Surgery department at Medical College of WisconsinBadi Rawashdeh MBBS Instructor in the Surgery department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
CryopreservationDatabases, Factual
Humans
Liver Transplantation
Perfusion
United Kingdom
