Faculty Collaboration Database

Pediatric health-related quality of life: Feasibility, reliability and validity of the PedsQL transplant module. Am J Transplant 2010 Jul;10(7):1677-85

Date

07/21/2010

Pubmed ID

20642689

DOI

10.1111/j.1600-6143.2010.03149.x

Scopus ID

2-s2.0-79551475212 (requires institutional sign-in at Scopus site)   51 Citations

Abstract

The measurement properties of the newly developed Pediatric Quality of Life Inventory (PedsQL) 3.0 Transplant Module in pediatric solid organ transplant recipients were evaluated. Participants included pediatric recipients of liver, kidney, heart and small bowel transplantation who were cared for at seven medical centers across the United States and their parents. Three hundred and thirty-eight parents of children ages 2-18 and 274 children ages 5-18 completed both the PedsQL 4.0 Generic Core Scales and the Transplant Module. Findings suggest that child self-report and parent proxy-report scales on the Transplant Module demonstrated excellent reliability (total scale score for child self-report alpha= 0.93; total scale score for parent proxy-report alpha= 0.94). Transplant-specific symptoms or problems were significantly correlated with lower generic HRQOL, supporting construct validity. Children with solid organ transplants and their parents reported statistically significant lower generic HRQOL than healthy children. Parent and child reports showed moderate to good agreement across the scales. In conclusion, the PedsQL Transplant Module demonstrated excellent initial feasibility, reliability and construct validity in pediatric patients with solid organ transplants.

Author List

Weissberg-Benchell J, Zielinski TE, Rodgers S, Greenley RN, Askenazi D, Goldstein SL, Fredericks EM, McDiarmid S, Williams L, Limbers CA, Tuzinkiewicz K, Lerret S, Alonso EM, Varni JW

Author

Stacee Lerret PhD Professor Hybrid in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Child
Child, Preschool
Feasibility Studies
Female
Health Status
Humans
Male
Organ Transplantation
Parents
Psychology, Child
Quality of Life
Reproducibility of Results
United States