Patterns, correlates, and barriers to medication adherence among persons prescribed new treatments for HIV disease. Health Psychol 2000 Mar;19(2):124-33
Date
04/13/2000Pubmed ID
10762096DOI
10.1037/0278-6133.19.2.124Scopus ID
2-s2.0-0033759605 (requires institutional sign-in at Scopus site) 588 CitationsAbstract
New treatments for HIV can improve immune functioning and decrease mortality. However, lapses in adherence may render these complex regimens ineffective. Sixty-three men and 9 women on highly active antiretroviral therapy completed measures of medication adherence, psychological characteristics, and barriers to adherence. HIV viral load, a health outcome measure of virus amount present in blood, was also obtained. The sample was 36% African American and 56% Caucasian, with 35% reporting disability. Nearly one third of patients had missed medication doses in the past 5 days, and 18% had missed doses weekly over the past 3 months. Frequency of missed doses was strongly related to detectable HIV viral loads. Depression, side-effect severity, self-efficacy, and social support distinguished patients with good and poor adherence. Barriers also varied with adherence level. Implications for interventions promoting HIV treatment adherence are discussed.
Author List
Catz SL, Kelly JA, Bogart LM, Benotsch EG, McAuliffe TLAuthors
Jeffrey A. Kelly PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinTimothy L. McAuliffe PhD Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultAntiviral Agents
Attitude to Health
Drug Administration Schedule
Drug Prescriptions
Female
HIV Seropositivity
Humans
Male
Patient Compliance
Retrospective Studies
Social Support
Surveys and Questionnaires
