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Contribution of Obstructive Sleep Apnea to Asthmatic Airway Inflammation and Impact of Its Treatment on the Course of Asthma. Sleep Med Clin 2024 Jun;19(2):261-274

Date

05/02/2024

Pubmed ID

38692751

DOI

10.1016/j.jsmc.2024.02.006

Scopus ID

2-s2.0-85187374866 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

Asthma and obstructive sleep apnea (OSA) are very common respiratory disorders in the general population. Beyond their high prevalence, shared risk factors, and genetic linkages, bidirectional relationships between asthma and OSA exist, each disorder affecting the other's presence and severity. The author reviews here some of the salient links between constituents of the alternative overlap syndrome, that is, OSA comorbid with asthma, with an emphasis on the effects of OSA or its treatment on inflammation in asthma. In the directional relationship from OSA toward asthma, beyond direct influences, multiple factors and comorbidities seem to contribute.

Author List

Ioachimescu OC

Author

Octavian C. Ioachimescu MD, PhD Vice Chair, Director, Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Asthma
Comorbidity
Humans
Inflammation
Sleep Apnea, Obstructive