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Dabrafenib for Pilocytic Astrocytoma With BRAF V599ins. JCO Precis Oncol 2024 May;8:e2400055

Date

05/23/2024

Pubmed ID

38781546

DOI

10.1200/PO.24.00055

Scopus ID

2-s2.0-85200505701 (requires institutional sign-in at Scopus site)

Abstract

This report highlights the first pediatric case of pilocytic astrocytoma with BRAF V599ins mutation, successfully treated with dabrafenib.

Author List

Tanaka R, Mrachek K, Arocho-Quinones E, Carlberg VM, Smith C, Kurzrock R, Deshmukh T

Authors

Elsa V. Arocho-Quinones MD Assistant Professor in the Neurosurgery department at Medical College of Wisconsin
Valerie M. Carlberg MD Associate Professor in the Dermatology department at Medical College of Wisconsin
Edward Kelly S. Mrachek MD Assistant Professor in the Pathology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Astrocytoma
Brain Neoplasms
Child
Female
Humans
Imidazoles
Male
Mutation
Oximes
Proto-Oncogene Proteins B-raf