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Recent developments of ionic liquids in oligosaccharide synthesis: the sweet side of ionic liquids. Carbohydr Res 2013 Jun 28;375:35-46

Date

05/21/2013

Pubmed ID

23685038

DOI

10.1016/j.carres.2013.04.011

Scopus ID

2-s2.0-84877833759 (requires institutional sign-in at Scopus site)   58 Citations

Abstract

The area of ionic liquid (IL) research has seen tremendous growth over the last few decades. The development of novel ILs with new and attractive physical and chemical properties has had a direct impact on organic synthesis. In particular, ILs have had many applications in carbohydrate chemistry including their use as solvents for dissolving high molecular weight carbohydrate polymers such as cellulose and as solvents and catalysts in oligosaccharide synthesis. In this area, ILs have been involved in protecting group manipulation reactions as well as glycosidic couplings leading to new methodologies and enhanced procedures. In addition, ILs have been successfully utilized as solution-phase purification supports. This review focuses on the most recent advances in the application of ILs to oligosaccharide synthesis. This is an emerging area that offers great promise at addressing some of the obstacles that remain on the path towards the automation of oligosaccharide synthesis.

Author List

Galan MC, Jones RA, Tran AT

Author

Rachel Jones Lipinski Research Scientist I in the Biochemistry department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Ionic Liquids
Molecular Structure
Oligosaccharides
Solvents