Early microstructure of white matter associated with infant attention. Dev Cogn Neurosci 2020 Oct;45:100815
Date
07/14/2020Pubmed ID
32658763Pubmed Central ID
PMC7358182DOI
10.1016/j.dcn.2020.100815Scopus ID
2-s2.0-85087591371 (requires institutional sign-in at Scopus site) 12 CitationsAbstract
Early infancy is characterized by rapid brain development that occurs alongside, and in response to, the development of cognitive and behavioral functions, including attention. Infants' ability to orient and sustain attention to stimuli develops in concert with refinement of the orienting network in frontoparietal regions of the brain. Infants (n = 97) underwent magnetic resonance imaging at one-month of age and data were fit to a diffusion tensor imaging model to calculate fractional anisotropy (FA) and radial diffusivity (RD), as well as to a neurite orientation dispersion and density imaging model to calculate intracellular volume fraction (νic). Infant attention was assessed at six months of age using a dynamic puppet task (Cuevas and Bell, 2014). Infants with higher FA in the corpus callosum and anterior cingulum showed increased orienting behaviors. Our findings indicate that increased microstructure of the white matter tracts in the orienting network may play a role in the early neurodevelopment of attentional orienting behaviors.
Author List
Dowe KN, Planalp EM, Dean DC 3rd, Alexander AL, Davidson RJ, Goldsmith HHAuthor
Kristin Dowe MS Assistant Professor in the Obstetrics and Gynecology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AttentionBrain
Female
Humans
Infant
Infant, Newborn
Male
White Matter
