Development of an immunocontraceptive vaccine. Current status. J Reprod Med 1999 Sep;44(9):759-65
Date
10/06/1999Pubmed ID
10509297Scopus ID
2-s2.0-0032830167 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
Development of an effective and modern contraceptive vaccine is a key factor in the global issue of regional population growth as well as agricultural, medical, economic and social development. A review was done of the current medical literature concerning development of an immunocontraceptive vaccine and relative molecular biology technology. Various approaches have been taken to identify candidate-specific antigens for immunocontraceptive development, such as sperm, zona pellucida and hormonal antigens. Suppressed fertility and the reversibility of these effects on mammalian species, including humans, have been demonstrated. The successful results obtained so far support the continued investigation for an effective immunocontraceptive vaccine.
Author List
Feng H, Sandlow JI, Sparks AE, Sandra AAuthor
Jay I. Sandlow MD Chair, Professor in the Urologic Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsAntigens
Contraception, Immunologic
Female
Hormones
Humans
Male
Spermatozoa
Vaccines
Zona Pellucida
