Postsurgical pyoderma gangrenosum after mastectomy with a familial component. J Surg Case Rep 2024 Oct;2024(10):rjae667
Date
10/23/2024Pubmed ID
39439812Pubmed Central ID
PMC11495327DOI
10.1093/jscr/rjae667Scopus ID
2-s2.0-85207419567 (requires institutional sign-in at Scopus site)Abstract
Postsurgical pyoderma gangrenosum (PSPG) is a rare, ulcerative skin condition that presents a diagnostic challenge due to its similar presentation to infectious etiologies in the postsurgical period-often leading to gratuitous and unnecessary surgery and antibiotic use. We report a 37-year-old female with breast cancer who received neoadjuvant chemotherapy and immunotherapy and underwent bilateral skin-sparing mastectomies who developed delayed bilateral mastectomy skin flap necrosis secondary to PSPG. This case had rare factors associated with the development of PSPG such as preoperative systemic therapy and a familial component. This case underscores the importance of early recognition of this rare disease and appropriate management of PSPG to prevent unnecessary interventions and ensure an optimal outcome.
Author List
Rogers CC, Nepper J, Holzem KE, Cortina CSAuthors
Chandler S. Cortina MD Associate Professor in the Surgery department at Medical College of WisconsinKassandra E. Holzem MD Assistant Professor in the Dermatology department at Medical College of Wisconsin
