Faculty Collaboration Database

Completion of Distress Screening and Correlates of Distress Score in Patients With Multiple Myeloma at Initial Evaluation at a Transplant Center. Eur J Haematol 2025 May;114(5):890-899

Date

02/17/2025

Pubmed ID

39957265

DOI

10.1111/ejh.14394

Scopus ID

2-s2.0-85219740848 (requires institutional sign-in at Scopus site)

Abstract

OBJECTIVES: We describe the completion of the National Comprehensive Care Network's distress thermometer (DT) survey for multiple myeloma (MM), quantify, and identify factors influencing distress score.

METHODS: We assessed DT completion for MM patients' first consultation at an academic center between January 1, 2015, and December 31, 2022. Multivariate logistic regression was conducted to identify factors associated with survey completion and distress.

RESULTS: Of 1011 new patients, 683 (68%) completed the DT survey. Noncompletion at initial consultation was associated with non-Hispanic Black patients [AOR 0.50 (95% CI 0.32-0.79), p = 0.003], socially vulnerable neighborhood residence [AOR 0.54 (95% CI 0.39-0.76), p = 0.0004], Karnofsky Performance Status < 90 [AOR 0.60 (95% CI 0.43-0.86), p = 0.005], and recent years of consult [AOR 0.38, (95% CI 0.28-0.52), p < 0.0001]. Nonrespondents were less likely to receive a subsequent autologous stem cell transplantation (71% vs. 79%, p < 0.01). The median distress score among respondents was 3% with 22% reporting 0 distress. Distress was associated with female sex [AOR 1.48, (95% CI 1.07-2.04), p = 0.017] and stage [stage 2 vs. stage 1, AOR 1.76 (95% CI 1.20-2.57), p = 0.004].

CONCLUSIONS: Disparities in nonrespondents of the DT survey at initial consultation suggest the limitations of relying on the screening tool to assess unmet needs among high-risk patients.

Author List

Estrada-Merly N, Wu JF, Pezzin LE, Nataliansyah MM, D'Souza A

Authors

Mochamad M. Nataliansyah MD, PhD Assistant Professor in the Surgery department at Medical College of Wisconsin
Liliana Pezzin PhD, JD Professor in the Institute for Health and Humanity department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Female
Hematopoietic Stem Cell Transplantation
Humans
Male
Middle Aged
Multiple Myeloma
Stress, Psychological
Surveys and Questionnaires