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Arthropathy of Down syndrome. Pediatrics 1990 Dec;86(6):931-6

Date

12/01/1990

Pubmed ID

2147471

Scopus ID

2-s2.0-0025678726   25 Citations

Abstract

A juvenile rheumatoid arthritis-like arthropathy has previously been documented in 12 patients with Down syndrome. An additional 9 patients are described and the literature is reviewed. It is unknown whether these patients have juvenile rheumatoid arthritis or a unique arthropathy in light of the genetic and immunologic abnormalities associated with Down syndrome. Most of the patients had a progressive course with polyarticular disease complicated by subluxations and a long lag time to diagnosis. The purpose of reporting these children is to increase awareness of this association and facilitate more appropriate and timely diagnosis of arthritis in Down syndrome patients.

Author List

Olson JC, Bender JC, Levinson JE, Oestreich A, Lovell DJ

Author

Judyann C. Olson MD Associate Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Arthritis, Rheumatoid
Child
Child, Preschool
Down Syndrome
Female
Humans
Male
jenkins-FCD Prod-480 9a4deaf152b0b06dd18151814fff2e18f6c05280