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Retrospective diagnosis of congenital cytomegalovirus infection and cortical maldevelopment. Neurology 2003 Sep 09;61(5):710-2

Date

09/10/2003

Pubmed ID

12963772

DOI

10.1212/wnl.61.5.710

Scopus ID

2-s2.0-0041834591 (requires institutional sign-in at Scopus site)   39 Citations

Abstract

Congenital cytomegalovirus (CMV) infection can cause malformations of cortical development (MCD). It is difficult to establish CMV as a cause of MCD several months postpartum. This can now be done by detection of CMV DNA in dried blood spots (DBS test) on Guthrie cards. The authors used DBS tests to assess 10 patients with MCD of unknown cause. Four of the 10 patients were positive for CMV.

Author List

Zucca C, Binda S, Borgatti R, Triulzi F, Radice L, Buttè C, Barkhaus PE, Barbi M

Author

Paul E. Barkhaus MD Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Cerebral Cortex
Child, Preschool
Cytomegalovirus Infections
Female
Humans
Infant
Magnetic Resonance Imaging
Male
Nervous System Malformations
Retrospective Studies