Evaluation of hematopoietic stem cell donors. Hematology Am Soc Hematol Educ Program 2005:469-75
Date
11/24/2005Pubmed ID
16304422DOI
10.1182/asheducation-2005.1.469Scopus ID
2-s2.0-33750569562 (requires institutional sign-in at Scopus site) 67 CitationsAbstract
Donation of hematopoietic stem cells, either through bone marrow or peripheral blood collection, is a generally safe procedure for healthy donors. Serious adverse events are uncommon and death is exceedingly rare. Nevertheless, all donors must be carefully evaluated and fully informed prior to donation. This should be done by clinicians having good understanding of the potential physical and psychological complications of donation and the factors that may increase these risks. Additionally, donors and graft products must be evaluated for the potential to transmit infections and other diseases to the recipient and to satisfy an increasing number of national and international regulatory requirements. Donors must be able to provide informed consent without coercion or pressure. Special attention to the clinical, psychological and social needs of pediatric donors is necessary.
Author List
Horowitz MM, Confer DLAuthor
Mary M. Horowitz MD, MS Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultChild
Communicable Disease Control
Communicable Diseases
Female
Hematopoietic Stem Cell Transplantation
Humans
Informed Consent
Male
Patient Selection
Risk Assessment
Sexual Behavior
Surveys and Questionnaires
Tattooing
Tissue Donors