Faculty Collaboration Database

Swallow-related cerebral cortical activity maps are not specific to deglutition. Am J Physiol Gastrointest Liver Physiol 2001 Apr;280(4):G531-8

Date

03/20/2001

Pubmed ID

11254478

DOI

10.1152/ajpgi.2001.280.4.G531

Scopus ID

2-s2.0-0034998251 (requires institutional sign-in at Scopus site)   88 Citations

Abstract

Cortical representation of swallow-related motor tasks has not been systematically investigated. In this study, we elucidated and compared these cortical representations to those of volitional swallow using block-trial and single-trial methods. Fourteen volunteers were studied by functional magnetic resonance imaging. Cortical activation during both swallowing and swallow-related motor tasks that can be performed independent of swallowing, such as jaw clenching, lip pursing, and tongue rolling, was found in four general areas: the anterior cingulate, motor/premotor cortex, insula, and occipital/parietal region corresponding to Brodmann's areas 7, 19, and 31. Regions of activity, volume of activated voxels, and increases in signal intensity were found to be similar between volitional swallow and swallow-related motor tasks. These findings, using both block-trial and single-trial techniques, suggest that cerebral cortical regions activated during swallowing may not be specific to deglutitive function.

Author List

Kern M, Birn R, Jaradeh S, Jesmanowicz A, Cox R, Hyde J, Shaker R

Author

Reza Shaker MD Assoc Provost, Sr Assoc Dean, Ctr Dir, Chief, Prof in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Brain Mapping
Cerebral Cortex
Deglutition
Female
Humans
Jaw
Lip
Magnetic Resonance Imaging
Male
Tongue