Osteoblastoma response to chemotherapy. Cancer 1991 Sep 01;68(5):999-1003
Date
09/01/1991Pubmed ID
1913494DOI
10.1002/1097-0142(19910901)68:5<999::aid-cncr2820680515>3.0.co;2-zScopus ID
2-s2.0-0025937637 (requires institutional sign-in at Scopus site) 24 CitationsAbstract
An 8-year-old boy had an osteoblastoma of the body of C2. After attempted excision, the tumor recurred rapidly and massively. The tumor shrank progressively after treatment with high-dose methotrexate, doxorubicin, and cisplatin. The patient has stopped treatment and been stable for 33 months. Surgical excision remains the treatment of choice for osteoblastoma. Chemotherapy may be useful in selected patients with a recurrent, aggressive tumor or in patients with surgically inaccessible disease.
Author List
Camitta B, Wells R, Segura A, Unni KK, Murray K, Dunn DAuthor
Annette D. Segura MD Adjunct Assistant Professor in the Pathology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Bone NeoplasmsCervical Vertebrae
Child
Dose-Response Relationship, Drug
Head and Neck Neoplasms
Humans
Male
Methotrexate
Osteoma, Osteoid